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Study of RMC-5127 in Patients With Advanced KRAS G12V-Mutant Solid Tumors

Study on KRAS G12V-Mutant Solid Tumors with RMC-5127

Recruiting
18 years and older
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates advanced KRAS G12V-mutant solid tumors. It evaluates the safety and tolerability of an investigational medication called RMC-5127.

The study focuses on understanding how the investigational medication works and its effects on the body. It assesses the medication's safety and how well it is tolerated by participants.

  • Who can participate: Adults aged 18 and older with advanced KRAS G12V-mutant solid tumors can participate. Key eligibility includes having a measurable tumor and adequate organ function.
  • Study details: Participants will take part in a study where they receive an investigational medication. Some participants may receive the medication alone, while others may receive it in combination with other treatments.
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Study details
    Non-small Cell Lung Cancer (NSCLC)
    Colorectal Cancer (CRC)
    Pancreatic Adenocarcinoma
    Pancreatic Ductal Adenocarcinoma (PDAC)
    PDAC
    CRC
    NSCLC
    Pancreatic Cancer
    Lung Cancer (NSCLC)
    Advanced Solid Tumors

NCT07349537

Revolution Medicines, Inc.

31 July 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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