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ORACLE: Observation of ResiduAl Cancer With Liquid Biopsy Evaluation

Clinical Study on Investigational Test for Detecting Recurrence in Early-Stage Solid Tumors

Recruiting
18 years and older
All
Phase N/A

This study investigates the use of a novel liquid biopsy test to detect recurrence in individuals who have been treated for early-stage solid tumors. The purpose of this study is to observe the relationship between test results and clinical outcomes.

The study evaluates the effectiveness of the liquid biopsy test in a healthcare setting. It explores the test's potential value in monitoring patients while considering cost factors.

  • Who can participate: Adults over 18 years who have been treated for early-stage solid tumors with curative intent and are undergoing regular follow-up for cancer recurrence can participate. Participants must consent to provide blood samples and share clinical data.
  • Study details: Participants will provide blood samples at enrollment and during follow-up visits for up to 5 years. The study involves sharing de-identified clinical data with researchers. A placebo is not involved in this study.
  • Study timelines: The study will last up to 5 years.
Study details
    Bladder Carcinoma
    Ureter Carcinoma
    Renal Pelvis Carcinoma
    Non-small Cell Lung Cancer
    Invasive Breast Carcinoma
    Cutaneous Melanoma
    Esophageal Carcinoma
    Gastroesophageal Junction Carcinoma
    Gastric Adenocarcinoma
    Pancreatic Adenocarcinoma
    Squamous Cell Carcinoma of the Head and Neck
    Epithelial Ovarian Carcinoma
    Fallopian Tube Carcinoma
    Endometrial Carcinoma
    Renal Cell Carcinoma
    Rectal Adenocarcinoma

NCT05059444

Guardant Health, Inc.

31 July 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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