Image

DETERMINE Trial Treatment Arm 04: Trastuzumab in Combination With Pertuzumab in Adult, Paediatric and Teenage/Young Adult Patients With Cancers With HER2 Amplification or Activating Mutations

Study on Investigational Medication for HER2 Amplified or Mutated Cancers

Recruiting
12 years and older
All
Phase 2/3
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates cancers with HER2 amplification or activating mutations.

The study evaluates the investigational medication's potential effectiveness and safety in treating different types of cancers with HER2 changes.

  • Who can participate: Participants must be 12 years or older with a confirmed diagnosis of a cancer having HER2 amplification or mutation.
  • Study details: Participants will receive an investigational medication and may also receive a placebo. An inactive substance that looks like the investigational medicine but does not contain any medicine.
Print
Study details
    Haematological Malignancy
    Colorectal Neoplasms
    Urinary Bladder Neoplasm
    Gallbladder Neoplasms
    Salivary Gland Neoplasm
    Lung Neoplasm
    Pancreatic Neoplasm
    Ovarian Neoplasms
    Prostatic Neoplasm
    Skin Neoplasm
    Solid Tumour

NCT05786716

Cancer Research UK

31 July 2026

Contact a study center
Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.