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Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors

Investigation of Safety and Tolerability of Investigational Medication

Recruiting
18 years and older
All
Phase 1

This study investigates the safety and tolerability of an investigational medication in patients with EGFR-driven advanced solid tumors. The study focuses on how patients respond to this treatment.

The purpose of this study is to evaluate the investigational medication both alone and in combination with another treatment. It looks at how safe the medication is for patients and how well they can tolerate it.

  • Who can participate: Adults with EGFR-driven advanced solid tumors and a performance status of 1 or less may participate. Participants must be willing to undergo biopsies.
  • Study details: Participants will receive either the investigational medication alone or in combination with another treatment. Some may receive a placebo.
Study details
    Head and Neck Squamous Cell Carcinoma
    Squamous Cell Carcinoma of Anal Canal
    Colorectal Cancer
    Squamous Cell Carcinoma of the Lung
    EGFR Amplification
    Epithelial Ovarian Cancer
    Pancreas Cancer
    Cutaneous Squamous Cell Carcinoma
    Head and Neck Neoplasms
    Carcinoma
    Squamous Cell
    Squamous Cell Carcinoma of Head and Neck

NCT04429542

Bicara Therapeutics

31 July 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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