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This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors

Investigation of Anti-LLT1 Antibody in Advanced Solid Tumors

Recruiting
18 years and older
All
Phase 1

This study investigates the use of an investigational medication for advanced solid tumors. The purpose of this study is to evaluate the effects of the investigational medication alone and in combination with another treatment.

The study focuses on understanding the safety and potential effects of the investigational medication. Researchers will evaluate how well the investigational medication is tolerated by participants.

  • Who can participate: Adults aged 18 and older with advanced solid tumors that have no standard treatment options or who are intolerant to these treatments can participate. Adequate organ function and other health criteria are required.
  • Study details: Participants will receive the investigational medication and may also receive a combination treatment. In some cases, a placebo may be used, which is an inactive substance that looks like the investigational medication but does not contain any medicine.
Study details
    Non Small Cell Lung Cancer
    Head and Neck Squamous Cell Carcinoma
    Pancreas Adenocarcinoma
    Biliary Tract Cancer
    Prostate Cancer
    Urothelial Carcinoma
    Colorectal Cancer
    Triple Negative Breast Cancer
    High Grade Ovarian Serous Adenocarcinoma
    Diffuse Large B Cell Lymphoma
    Renal Cell Cancer Metastatic

NCT06451497

Zumutor Biologics Inc.

31 July 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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