This study investigates the use of endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) for treating upper gastrointestinal tract lesions. The study focuses on patients with pancreatic or adrenal tumors who receive EUS-RFA as part of their standard clinical care.

The study evaluates the long-term clinical effectiveness and quality of life outcomes for patients undergoing EUS-RFA. It examines factors such as patient satisfaction, safety, and technical success of the procedure.

• Who can participate: Adults with pancreatic or adrenal lesions suitable for the investigational procedure can participate. Participants must sign informed consent.
• Study details: Participants will undergo an investigational procedure where a needle is guided into the tumor using an endoscope and ultrasound. Radiofrequency energy is used to destroy tumor cells. They will have follow-up visits and complete questionnaires on satisfaction and quality of life.
• Study timelines: The study will last up to 5 years for each participant.