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Neoadjuvant Triple Therapy for (Borderline) Resectable Pancreatic Cancer (PREOPANC-5)

Study of Neoadjuvant Triple Therapy in Resectable Pancreatic Cancer

Recruiting
18 years and older
All
Phase 1/2

This study investigates neoadjuvant triple therapy for patients with resectable pancreatic cancer. The purpose of this study is to see if this approach can improve outcomes for these patients.

The study evaluates the safety and effectiveness of combining chemotherapy, immunotherapy, and radiotherapy before surgery. It looks at whether this combination can improve survival rates for patients with resectable pancreatic cancer.

  • Who can participate: Adults aged 18 and older with confirmed pancreatic adenocarcinoma that is resectable or borderline resectable can participate. Key eligibility includes a good performance status and the ability to undergo multiple treatments. Participants with metastatic or locally advanced pancreatic cancer are not eligible.
  • Study details: Participants will receive chemotherapy, immunotherapy, and radiotherapy before surgery.
Study details
    Localized Pancreatic Adenocarcinoma
    Borderline Resectable Pancreatic Adenocarcinoma
    Resectable Pancreatic Adenocarcinoma

NCT06384560

Amsterdam UMC, location VUmc

31 July 2026

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