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Metarrestin (ML-246) in Subjects With Metastatic Solid Tumors

Investigational Medication for Metastatic Solid Tumors

Recruiting
12-120 years
All
Phase 1

This study investigates metastatic solid tumors. The purpose of this study is to explore the effects of an investigational medication on these tumors.

The study evaluates the safety and possible effectiveness of the investigational medication in shrinking tumors.

  • Who can participate: Adults aged 18 and older with pancreatic, breast, or other solid tumors not cured by standard therapies, and children aged 12-17 with solid tumors other than rhabdomyosarcoma may participate.
  • Study details: Participants will take the investigational medication by mouth.
Study details
    Advanced Solid Tumors
    Metastatic Pancreatic Cancer
    Pediatric Solid Tumor
    Advanced Breast Cancer
    Malignant Peripheral Nerve Sheath Tumor
    Colorectal Neoplasms

NCT04222413

National Cancer Institute (NCI)

17 October 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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