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Examining Safety, Efficacy and Feasibility of Preoperative Propranolol in Patients With PDAC.

Investigating Preoperative Propranolol for Pancreatic Cancer Surgery

Recruiting
18 years and older
All
Phase 2

This study investigates preoperative propranolol in patients with pancreatic cancer. The purpose of this study is to explore the effects of propranolol before surgery.

Researchers will evaluate the safety and effectiveness of propranolol in reducing anxiety and its impact on tumor-related changes. The study will also look at how propranolol affects heart rate variability.

  • Who can participate: Adults 18 years or older with suspected surgically resectable pancreatic cancer who can provide written consent may participate. Certain medical conditions and recent use of beta-blockers or specific medications are exclusion factors.
  • Study details: Participants will take propranolol or a placebo before surgery. A placebo is an inactive substance that looks like the investigational medicine but does not contain any medicine.
Study details
    Pancreatic Cancer
    Surgery

NCT06145074

Zealand University Hospital

8 April 2026

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