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The Value of Molecular Residual Disease Monitoring Based on ctDNA in Resected Pancreatic Cancer

Investigating Molecular Residual Disease Monitoring in Resected Pancreatic Cancer

Recruiting
18 years and older
All
Phase N/A
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates the value of monitoring molecular residual disease (MRD) based on circulating tumor DNA (ctDNA) in resected pancreatic cancer.

The study evaluates the prognostic value of baseline MRD and the role of MRD dynamic changes after treatment in guiding further treatment decisions.

  • Who can participate: Adults aged 18 and older with pancreatic cancer who have undergone curative-intent surgery and have an ECOG performance status score of 2 or less can participate. Participants should have an expected survival time of at least 3 months.
  • Study details: Participants will provide peripheral blood samples for MRD testing before starting adjuvant chemotherapy and at the first imaging assessment after chemotherapy.
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Study details
    Pancreatic Cancer
    Resectable Carcinoma

NCT05802407

Peking Union Medical College Hospital

8 April 2026

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