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NALIRI-XELOX+AK104 for First-line Treatment of Advanced PDAC

Study on Advanced Pancreatic Ductal Adenocarcinoma

Recruiting
18 years and older
All
Phase 2

This study investigates advanced pancreatic ductal adenocarcinoma. It evaluates how well the investigational medication works and its safety when used with other treatments.

The purpose of this study is to assess the effects of the investigational medication combined with other treatments. This study evaluates the safety and effectiveness of this combination for people with this condition.

  • Who can participate: Adults aged 18 and older with confirmed pancreatic ductal adenocarcinoma can participate. Participants must not have had prior systemic treatment and must meet certain health criteria.
  • Study details: Participants will take part in a study where they receive an investigational medication. Some participants may receive a placebo, an inactive substance that looks like the investigational medicine but does not contain any medicine.
Study details
    Nanoliposomal Irinotecan
    Cadonilimab
    Oxaliplatin
    Capecitabine
    First-Line
    Advanced Cancer
    Pancreatic Adenocarcinoma
    Drug Use

NCT06405490

Cancer Institute and Hospital, Chinese Academy of Medical Sciences

31 July 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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