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A Study of NI-1801 in Patients with Mesothelin Expressing Solid Cancers

Investigation of an Investigational Medication for Mesothelin Expressing Solid Cancers

Recruiting
18 years and older
All
Phase 1

This study investigates mesothelin expressing solid cancers. The purpose of this study is to evaluate an investigational medication in patients with advanced, metastatic, or recurrent solid malignancies that express mesothelin.

The study focuses on evaluating the safety and effectiveness of the investigational medication. It will assess how well patients tolerate the treatment and determine the best dose for future studies.

  • Who can participate: Adults 18 years and older with mesothelin expressing cancers can participate. Participants must have had at least one prior treatment and meet specific health criteria.
  • Study details: Participants will receive the investigational medication in cycles and may also receive a placebo, an inactive substance that looks like the investigational medicine.
  • Study timelines: The study will last 12 months.
Study details
    Epithelial Ovarian Cancer
    Triple Negative Breast Cancer
    Non-squamous Non-small-cell Lung Cancer
    Pancreatic Adenocarcinoma (ductal Adenocarcinoma)
    Endometrioid Ovarian Cancer

NCT05403554

Light Chain Bioscience - Novimmune SA

30 July 2026

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