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Lead-212 PSV359 Therapy for Patients With Solid Tumors

Investigational Therapy for Solid Tumors Using Alpha-Particle Radiation

Recruiting
18-90 years
All
Phase 1/2

This study investigates solid tumors that are Fibroblast Activation Protein (FAP)-positive. The purpose of this study is to evaluate an investigational therapy using a specific type of radiation for patients with these tumors.

The study is focused on exploring the safety and effectiveness of a targeted radiation therapy. It looks into how well the therapy works and how safe it is for patients with FAP-positive tumors.

  • Who can participate: Adults aged 18 and older with a positive scan showing tumor uptake, and a solid tumor that is locally advanced or metastatic, may be eligible. Participants must have satisfactory organ function and a life expectancy of more than 3 months.
  • Study details: Participants will receive an investigational medication that uses a type of radiation aimed at treating tumors.
Study details
    Pancreatic Ductal Adenocarcinoma
    Gastric Cancer
    Esophageal Cancer
    Colorectal Cancer
    Ovarian Cancer
    Head and Neck Cancer
    Sarcoma
    Mesothelioma

NCT06710756

Perspective Therapeutics

17 October 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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