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Zimberelimab and Quemliclustat in Combination With Chemotherapy for the Treatment of Patients With Borderline Resectable and Locally Advanced Pancreatic Adenocarcinoma

Study on Treatment for Pancreatic Cancer

Recruiting
18 years and older
All
Phase 1/2

This study investigates pancreatic adenocarcinoma. The purpose of this study is to explore how a combination of investigational medications and chemotherapy works in patients with this condition.

The study evaluates the safety and effectiveness of combining investigational medications with chemotherapy. It focuses on understanding how these treatments work together to affect the condition.

  • Who can participate: Adults aged 18 and older with untreated pancreatic adenocarcinoma that is borderline resectable or locally advanced can participate.
  • Study details: Participants will receive investigational medications and chemotherapy through infusions. Some participants may receive a placebo, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.
Study details
    Borderline Resectable Pancreatic Adenocarcinoma
    Locally Advanced Pancreatic Ductal Adenocarcinoma

NCT05688215

Jonsson Comprehensive Cancer Center

31 July 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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