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Targeted Pathway Inhibition in Patients With Pancreatic Cancer

Investigating Targeted Pathway Inhibition for Pancreatic Cancer

Recruiting
18 years and older
All
Phase 0

This study investigates pancreatic cancer. The purpose of this study is to explore how different investigational medications work in patients with this condition.

The study evaluates the safety and tolerability of the investigational medications. It also looks at changes in tumor biology and potential biomarkers.

  • Who can participate: Adults aged 18 and older with pancreatic cancer may participate. Eligibility includes having resectable, borderline resectable, locally-advanced, or metastatic adenocarcinoma of the pancreas and the ability to undergo tumor biopsies.
  • Study details: Participants will receive an investigational medication. They will undergo biopsies or surgery as part of the study.
Study details
    Locally Advanced Pancreatic Ductal Adenocarcinoma
    Metastatic Pancreatic Ductal Adenocarcinoma
    Stage II Pancreatic Cancer AJCC v8
    Stage III Pancreatic Cancer AJCC v8
    Stage IV Pancreatic Cancer AJCC v8
    Unresectable Pancreatic Ductal Adenocarcinoma
    Borderline Resectable Pancreatic Ductal Adenocarcinoma
    Resectable Pancreatic Ductal Adenocarcinoma

NCT04005690

OHSU Knight Cancer Institute

12 September 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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