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Pegcetacoplan in Combination With Modified FOLFIRINOX for the Treatment of Metastatic Pancreatic Ductal Adenocarcinoma

Investigating Pegcetacoplan with mFOLFIRINOX for Metastatic Pancreatic Ductal Adenocarcinoma

Recruiting
18 years and older
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates the treatment of metastatic pancreatic ductal adenocarcinoma. It evaluates the effects of pegcetacoplan combined with mFOLFIRINOX chemotherapy.

The study focuses on assessing the safety and potential effectiveness of this combination therapy. It also examines the impact of pegcetacoplan on preventing major thrombotic events in patients.

  • Who can participate: Adults aged 18 and older with confirmed metastatic pancreatic ductal adenocarcinoma may participate. Eligibility includes a good performance status and specific blood test results.
  • Study details: Participants will receive pegcetacoplan and mFOLFIRINOX chemotherapy with regular monitoring through blood tests and imaging. A placebo is not used in this study.
  • Study timelines and visits: The study will last up to 8 cycles. The study requires 8 visits.
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Study details
    Metastatic Pancreatic Ductal Adenocarcinoma
    Stage IV Pancreatic Cancer AJCC v8

NCT07214298

Roswell Park Cancer Institute

29 August 2026

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