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A Phase I Clinical Study of QLC1101 in Patients With Advanced Solid Tumors

Study of Investigational Medication for Advanced Solid Tumors with KRAS G12D Mutation

Recruiting
18 years and older
All
Phase 1
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates advanced solid tumors with a KRAS G12D mutation. It will explore how the investigational medication affects these tumors.

The study focuses on evaluating the safety, tolerability, and preliminary effectiveness of the investigational medication in people with this specific mutation.

  • Who can participate: Adults with advanced solid tumors and a KRAS G12D mutation who have tried or cannot tolerate standard treatments may participate. Participants must have an ECOG performance score of 0 or 1.
  • Study details: Participants will take an investigational medication orally. The study will assess how the body processes the medication and its effects on the tumor. An inactive substance that looks like the investigational medication but does not contain any medicine may be used for comparison.
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Study details
    Non-small Cell Lung Cancer
    Colorectal Cancer
    Pancreatic Cancer
    Solid Tumor

NCT06403735

Qilu Pharmaceutical Co., Ltd.

8 April 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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