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Cryoablation Combined With the Dual-Function Antibody PD-1/CTLA-4 for the Treatment of LAPC Following Failure of First-Line AG Therapy

Investigating Cryoablation and Antibody Therapy for Locally Advanced Pancreatic Cancer

Recruiting
18 years and older
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates the use of cryoablation combined with a dual-function antibody for the treatment of locally advanced pancreatic cancer.

This study evaluates the effectiveness and safety of this approach as a second-line therapy option.

  • Who can participate: Adults aged 18 and older with locally advanced pancreatic cancer who have experienced failure with first-line AG therapy may be eligible. Participants must have adequate organ function and an ECOG performance status of 0 to 2.
  • Study details: Participants will undergo cryoablation combined with antibody therapy. An inactive substance that looks like the investigational medicine but does not contain any medicine may be used as a placebo.
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Study details
    Pancreatic Adenocarcinoma Locally Advanced

NCT07306286

Ruijin Hospital

30 July 2026

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