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HRS-4642 in Combination With Nimotuzumab and Chemotherapy for BRPC With KRAS G12D Mutation

Efficacy of Investigational Medication and Nimotuzumab with Chemotherapy for Borderline Resectable Pancreatic Cancer with KRAS G12D Mutation

Recruiting
18-75 years
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates borderline resectable pancreatic cancer with the KRAS G12D mutation. The purpose of this study is to evaluate the combination of an investigational medication with Nimotuzumab and chemotherapy.

The study focuses on evaluating the effectiveness and safety of the treatment combination. It examines how well the treatment works and its tolerability for patients.

  • Who can participate: Adults aged 18 to 75 with borderline resectable pancreatic cancer and a KRAS G12D mutation can participate. Participants must have good organ function and no prior systemic anti-tumor therapy.
  • Study details: Participants will receive an investigational medication with Nimotuzumab and chemotherapy.
  • Study timelines and visits: The study will last 12 weeks. The study requires 8 visits.
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Study details
    Borderline Resectable Pancreatic Adenocarcinoma

NCT07240766

Zhejiang University

30 July 2026

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