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Hepatic Arterial Infusion of Sodium Bicarbonate (NaHCO3) Combined With NASOX Regimen and Programmed Death-1 (PD-1) Inhibitors for Pancreatic Cancer Liver Metastases

Study of Sodium Bicarbonate and NASOX Regimen with PD-1 Inhibitors for Pancreatic Cancer Liver Metastases

Recruiting
18 years and older
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates pancreatic cancer liver metastases. It explores the use of a combination therapy to manage this condition.

The study evaluates the safety and effectiveness of a treatment that includes Sodium Bicarbonate, NASOX chemotherapy, and PD-1 inhibitors. It looks into how these treatments work together to improve patient outcomes.

  • Who can participate: Adults aged 18 years and older with confirmed pancreatic cancer that has spread to the liver can participate. They must have a good performance status and adequate organ function.
  • Study details: Participants will receive a combination therapy including Sodium Bicarbonate and NASOX regimen, along with PD-1 inhibitors. A placebo may be used, which is an inactive substance that looks like the investigational medicine but does not contain any medicine.
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Study details
    Pancreatic Neoplasms
    Hepatic Metastasis of Pancreatic Cancer

NCT07504471

Ruijin Hospital

31 July 2026

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