This study investigates advanced solid malignancies. It evaluates the investigational medication both as a standalone treatment and in combination with other anti-cancer agents.
The purpose of this study is to assess the safety, tolerability, and preliminary effectiveness of the investigational medication. It also looks at how the body processes and responds to the medication.
- Who can participate: Adults aged 18 and older with progressive advanced solid malignancies and adequate organ function may participate. Participants must have no significant health deterioration and meet specific genetic mutation criteria.
- Study details: Participants will take the investigational medication alone or with other treatments. A placebo may be used in some parts of the study.
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