This study investigates the use of higher dose radiation therapy in patients with locally advanced pancreatic cancer. The purpose of this study is to compare the effects of dose-escalated radiation therapy to usual care options, such as additional chemotherapy or standard lower-dose radiation therapy.
The study evaluates whether the dose-escalated radiation therapy can improve survival rates. It focuses on assessing safety, effectiveness, and quality of life outcomes for patients receiving this treatment.
- Who can participate: Adults aged 18 and older with locally advanced pancreatic cancer who have completed 4-6 months of chemotherapy may be eligible. Participants must have stable disease and meet specific health criteria before joining the study.
- Study details: Participants will receive either standard care treatments or higher dose radiation therapy. The study includes regular imaging and blood tests. A placebo is not used in this study.
- Study timelines: The study will last 5 years.