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Brodalumab in the Treatment of Immune-Related Adverse Events

Investigational Medication for Managing Immune-Related Adverse Events Post-Cancer Immunotherapy

Recruiting
18 years and older
All
Phase 1

This study investigates the use of an investigational medication for treating immune-related adverse events in patients who have received cancer immunotherapy.

The study evaluates the safety and effectiveness of the investigational medication in managing these adverse events. It focuses on how well the medication can improve and resolve symptoms in affected patients.

  • Who can participate: Adults over 18 years of age with suspected IL-17 mediated immune-related adverse events are eligible. Participants should have been treated or intended to be treated with systemic steroids and must not be receiving curative cancer treatment.
  • Study details: Participants will receive the investigational medication through injections over 24 weeks. They will attend regular visits to monitor their response and report any changes in symptoms. A placebo may be used for comparison.
  • Study timelines and visits: The study will last 36 weeks. The study requires 9 visits.
Study details
    Breast Cancer
    Esophageal Cancer
    Kidney Cancer
    Lung Cancer
    Thyroid Cancer
    Gynecologic Cancer
    Pancreatic Cancer
    Stomach Cancer
    Brain Tumor
    Colon Cancer
    Rectal Cancer
    Head and Neck Cancer
    Oral Cancer
    Liver Cancer
    Skin Cancer
    Prostate Cancer
    Testicular Cancer
    Solid Tumor

NCT06673329

Brian Henick, MD

31 July 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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