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A Phase I/II Trial of UCB4594 in Participants With Advanced Cancer

Investigating the Safety and Impact of an Investigational Medication in Advanced Cancer

Recruiting
18 years and older
All
Phase 1/2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study investigates advanced cancer. The purpose of this study is to explore the effects of an investigational medication on cancer cells.

The study evaluates the safety and effects of the investigational medication. Researchers are looking at how the medication interacts with cancer cells and its overall impact.

  • Who can participate: Adults aged 18 years and older with advanced solid tumors that are not responding to standard treatments can participate. Participants must have measurable disease, a life expectancy of at least 12 weeks, and an Eastern Cooperative Oncology Group performance status of 0 or 1.
  • Study details: Participants will receive the investigational medication, which may be given alone or with other anti-cancer drugs.
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Study details
    Advanced Solid Tumours
    Squamous Cell Carcinoma of Head and Neck
    Carcinoma
    Non-Small-Cell Lung
    Colorectal Neoplasms
    Triple Negative Breast Neoplasms
    Carcinoma
    Renal Cell (Clear Cell Only)
    Esophageal Neoplasms
    Stomach Neoplasms (Excluding Gastrointestinal Stromal Tumors)
    Uterine Cervical Neoplasms
    Ovarian Neoplasms
    Pancreatic Neoplasms

NCT06380816

Cancer Research UK

31 July 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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