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A Study of MGC026 in Participants With Advanced Solid Tumors

Research Study for Advanced Solid Tumors

Recruiting
18 years and older
All
Phase 1

This study investigates the use of an investigational medication in people with advanced solid tumors. The purpose of this study is to understand how the body processes the medication and to check for any side effects.

The study evaluates the safety and tolerability of the investigational medication. Researchers will also look into how the medication affects the tumors.

  • Who can participate: Adults 18 years and older with advanced solid tumors may participate. Key eligibility includes adequate health status and availability of tumor tissue samples.
  • Study details: Participants will receive the investigational medication through an IV infusion. They may receive up to 35 treatments if there are no severe side effects and the cancer does not progress. A placebo, an inactive substance that looks like the investigational medicine but does not contain any medicine, may be used for comparison.
Study details
    Advanced Solid Tumor
    Advanced Cancer
    Metastatic Cancer
    Squamous Cell Carcinoma of Head and Neck
    Non Small Cell Lung Cancer
    Small-cell Lung Cancer
    Bladder Cancer
    Sarcoma
    Endometrial Cancer
    Melanoma
    Castration Resistant Prostatic Cancer
    Cervical Cancer
    Colorectal Cancer
    Gastric Cancer
    Gastro-esophageal Cancer
    Pancreas Cancer
    Clear Cell Renal Cell Carcinoma
    Hepatocellular Carcinoma
    Platinum-resistant Ovarian Cancer
    Breast Cancer
    Ovarian Cancer
    Esophageal Squamous Cell Cancer (SCC)

NCT06242470

MacroGenics

15 August 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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