**Sickle Cell Kidney Biorepository Study** Sickle Cell Disease (SCD) and Sickle Cell Trait (SCT) can harm the kidneys. This study stores blood and urine samples from people with SCD and SCT to help researchers learn how kidney disease starts and gets worse. The samples are kept safe and linked to medical records. This helps scientists find early signs of kidney problems and create better treatments. Chronic Kidney Disease (CKD) is common and serious in people with SCD and appears earlier than in others. Sickle Cell Trait is also a risk factor for CKD, but we still have much to learn about why and how it progresses. **Key Points:** - **Eligibility:** Must be 18-65 years old, not pregnant, and have certain kidney function levels. - **Commitment:** Involves giving blood and urine samples. - **Purpose:** Helps find better ways to protect kidney health in those with Sickle Cell conditions. For more information or to see if you qualify, please contact the research team.