Sickle Cell Disease (SCD) is a genetic disorder where red blood cells become stiff and can block blood flow. This study looks at whether regular red blood cell (RBC) transfusions help pregnant women with SCD avoid health problems. Some women will get these transfusions, while others will get the usual care. The study lasts from the time they are pregnant until two months after birth, or about 8-10 months. RBC transfusion is the standard treatment, but it's not clear if it helps prevent pregnancy problems in women with SCD. This study aims to find out if regular transfusions reduce complications like pain crises and organ damage during pregnancy.

• Length of study: 8-10 months.
• You may receive regular blood transfusions.
• Must be between 6-20 weeks pregnant to join.