Sickle Cell Disease (SCD) is a genetic blood disorder affecting many children, mostly Black, in the U.S. It causes severe pain crises, leading to frequent emergency room visits. These crises occur when blood cells become sickle-shaped and block blood flow, causing pain. The National Heart, Lung, and Blood Institute, along with the American Society of Hematology, have guidelines for treating this pain quickly. However, these guidelines are not always followed, often due to structural racism, which refers to societal systems that disadvantage certain racial groups.

This study aims to improve care for children with SCD during these pain crises by using specific treatment plans in the emergency department. The goal is to ensure faster and more effective pain relief.

• Study focuses on children with uncomplicated pain crises.
• Participants must have SCD and receive at least one opioid.
• Excludes those with fever, acute chest syndrome, or sickle cell trait.