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Stroke Prevention in Nigeria 2 Trial

"Join our Nigerian trial to help prevent strokes."

Recruiting
5-12 years
All
Phase 4

This study aims to see if a medicine called hydroxyurea can prevent strokes in kids with sickle cell anemia (SCA) in Nigeria. Sickle cell anemia is a blood disorder that makes red blood cells sickle-shaped and can cause pain and strokes. Regular blood transfusions, a common stroke prevention method, aren't practical in Nigeria. So, the study is testing hydroxyurea, a pill that might help prevent strokes without needing transfusions.

Children aged 5-12 years with sickle cell anemia are invited to join the study. They must have certain blood test results and be able to swallow pills. Kids who have had a stroke before or have other serious health issues can't join.

  • *Study lasts for 2.5 years with check-ups every 3 months.*
  • *Participants will receive hydroxyurea, and their health will be monitored closely.*
  • *The study aims to make stroke prevention more accessible and affordable.*
Study details
    Sickle Cell Disease
    Stroke

NCT06526117

Vanderbilt University Medical Center

17 April 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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