**Zinc Supplementation in Sickle Cell Disease Study** This study is for people with Sickle Cell Disease (SCD), a condition where red blood cells are shaped like sickles. These cells can cause health problems, including weak bones. The study looks at how zinc, a mineral important for healthy bones, affects people with SCD. **Study Details:** - **Participants:** 34 people with SCD, aged 15-40. - **Duration:** 16 weeks total; 4 weeks of normal care and 12 weeks taking zinc. - **Process:** Participants are randomly given either 25 or 40 mg of zinc daily. Two blood tests are done at the start, then zinc is taken for 12 weeks. The study checks how zinc helps bones. **Eligibility:** - Must be 15-40 years old and have SCD. - Can’t be on zinc supplements or certain other treatments. - Must be able to swallow pills. **Key Points:** - **Length:** 16 weeks total. - **Visits:** Blood tests at the start, zinc supplementation for 12 weeks. - **Risks/Compensation:** Not specified; discuss with the study team. This study helps find the right zinc dose for future research on improving bone health in SCD patients.