Study on Spleen Functions and Diseases The spleen is an organ that helps the body fight diseases and filter blood. However, we still don't fully understand how it works. This study aims to learn more about the spleen by studying how it handles changes in blood cells and its role in diseases like malaria. Adults planning to have surgery involving the spleen (like splenectomy, where part or all of the spleen is removed) can join the study. Blood samples will be taken before or during surgery, and the spleen or its parts will be collected for analysis. The spleen will be washed with a special fluid to study its response to different conditions. These samples will help researchers understand spleen functions better and check if certain substances can help treat related diseases.

• Participants must already be undergoing spleen-related surgery.
• Blood and spleen samples will be used for research purposes.
• You can opt out if you don't want your samples used.

Note: Participation involves use of surgical samples and does not include additional medical interventions.