This study is about collecting blood samples from people to help find new treatments for sickle cell disease. Sickle cell disease affects red blood cells, which are responsible for carrying oxygen in the body. People who are healthy or have sickle cell disease can participate. If you join, you'll need to be at least 18 years old. The study takes place at the National Institutes of Health, and you will be asked to give a small blood sample—about two teaspoons. If you have special red blood cell features, you might be asked to give another sample later. The total amount of blood taken will not exceed 50 ml over eight weeks for adults or 7 cc over six weeks for children. The researchers hope to find new drugs to help treat sickle cell disease.

• Participants must be at least 18 years old.
• Expect a one- to two-hour outpatient visit with blood donation.
• Potential for multiple visits if you have unique blood features.