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Wheat-free Diet in the Treatment of Sjogren's Syndrome

Trying a wheat-free diet for Sjogren's Syndrome research study.

Recruiting
18-65 years
All
Phase N/A

Wheat-free Diet in Sjogren's Syndrome Study

This study explores if a wheat-free diet can help people with Sjogren's Syndrome (SS). SS is an autoimmune disease where the body's immune system attacks its own glands, causing dryness, especially in the mouth and eyes. Some people might have non-celiac wheat sensitivity (NCWS), which means wheat can bother them even if they don't have celiac disease. The study will see if avoiding wheat helps reduce inflammation (swelling) and improves symptoms in people with SS.

The study compares two groups: one avoids wheat and cow's milk, and the other avoids rice and turkey for two months. Then, wheat is reintroduced to see if symptoms return. This helps understand if wheat affects SS symptoms.

  • Duration: The study lasts several months, with different diet phases.
  • Visits: Participants have multiple check-ups and tests.
  • Participation: You must be over 18 and under 65, without certain other health conditions.

Results will show if a wheat-free diet could be a helpful treatment for SS.

Study details
    Sjogren's Syndrome
    Non-celiac Gluten Sensitivity

NCT05644795

University of Palermo

17 April 2026

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