The **STAR Trial** is a study to test the safety and effectiveness of the Siegel™ TAVR System for people with *severe aortic stenosis*. Aortic stenosis is a heart problem where the *aortic valve* doesn't open fully, which can make it hard for blood to flow from the heart. The study involves a procedure called *transcatheter aortic valve replacement* (TAVR), where a new valve is placed in the heart without open-heart surgery. To join, you must be 18 or older with severe aortic stenosis and able to have TAVR. Some people can't join if they have other heart problems or certain health conditions. **Key Points:** - Study involves TAVR, a less invasive procedure than open-heart surgery. - Participants need to attend all follow-up visits and understand the study requirements. - Risks include those related to heart procedures, and there are specific health conditions that might exclude participation. Important: Participation requires understanding and agreeing to the procedures, as well as meeting specific health criteria. Always discuss with your doctor to see if this study is right for you.