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Efficacy of NBI-1117568 in Preventing Relapse in Adults With Schizophrenia

Study on NBI-1117568 for preventing schizophrenia relapse in adults.

Recruiting
18-65 years
All
Phase 3
**Study Overview:** This study aims to test a new medicine called NBI-1117568 to see if it can help prevent schizophrenia symptoms from coming back in adults. Schizophrenia is a mental illness that can cause changes in thinking, feeling, and behavior. The study compares the medicine to a placebo, which is a pill with no active medicine, to check its effectiveness. **Key Criteria:** - Adults with schizophrenia who have responded well to other antipsychotic medicines (except clozapine) can join. - Participants should not have severe uncontrolled health conditions or have been in a psychiatric hospital for a long time recently. - Participants can't have started or changed therapy treatments just before or during the study. **Important Points:** - **Duration and Visits:** Participants will first receive open-label treatment, then be observed for relapse prevention. - **Compensation:** There might be potential compensation for participation. - **Risks:** Possible risks include those typical for new medicine trials, such as side effects or no improvement in symptoms.

Note: Detailed criteria and other conditions apply. Consult with the study team for more information.

Study details
    Schizophrenia

NCT07227818

Neurocrine Biosciences

10 October 2026

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A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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