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PREvention of CardIovascular and DiabEtic kidNey Disease in Type 2 Diabetes

Join a trial to prevent heart and kidney issues in diabetes.

Recruiting
40-80 years
All
Phase 4
  • Simplified description (AI rewritten)
  • Technical description (Original)

PRECIDENTD is a study for people with type 2 diabetes (T2D) who have heart disease or are at high risk. The study will compare two treatments: sodium-glucose cotransporter-2 inhibitor (SGLT2i) and glucagon-like peptide-1 receptor agonists (GLP-1RA). These are medicines that help control blood sugar. The study will follow 6,000 participants to see how they prevent heart attacks, strokes, and kidney problems.

Participants must have T2D and either established heart disease or be at high risk. They must agree to take one of the study medications and not start the other unless advised by their doctor.

  • The study will last until 2028, and participants will be monitored for various health events.
  • Participants need to be willing to stop their current diabetes medication if it includes SGLT2i or GLP-1RA.
  • Participants must agree to share their health information for the study.

People with other types of diabetes, recent cancer, or certain health conditions are not eligible. Participants need to afford their medication through their insurance and must use birth control if needed.

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Study details
    Type2Diabetes
    ASCVD

NCT05390892

Brigham and Women's Hospital

10 October 2026

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What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

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Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

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The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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