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Comparison of Uncomplicated Candidemia Therapy Duration in Children

Studying candidemia treatment duration for children.

Recruiting
120 years and older
All
Phase N/A

This clinical trial is studying how long children with a type of yeast infection in the blood, called *uncomplicated candidemia*, need antifungal medicine. **Antifungal medicine** helps fight infections caused by fungi, which are similar to molds. The study compares two different treatment lengths: one group gets 7 more days of antifungal treatment (**standard-course**), while the other group stops after the first 7 days (**short-course**). The goal is to see if the shorter treatment works just as well as the longer one.

Key Points:

  • Children will be part of the study for about 21 days after starting the trial.
  • Participants must have already taken 7 days of antifungal medication with no signs of the infection spreading.
  • The study is only for children older than 120 days but younger than 18 years.

To join, children should not be expecting a drop in white blood cells (neutropenia) and shouldn't be pregnant or have certain medical devices. This study helps doctors understand if less medicine is just as good in treating these infections in children.

Study details
    Invasive Candidiasis

NCT05763251

Arkansas Children's Hospital Research Institute

17 October 2026

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