Image

MDMA-Assisted Massed Exposure Therapy for PTSD

MDMA therapy trial for PTSD support and research.

Recruiting
21-70 years
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study looks at using a drug called **MDMA** with a type of therapy called **Massed Prolonged Exposure (PE)** to help adults with **Posttraumatic Stress Disorder (PTSD)**. PTSD is a mental health condition that happens after experiencing a scary or dangerous event. In this research, 95 people will be randomly chosen to get either MDMA or a placebo (a pill that doesn’t have the medicine) during therapy. The study will see if MDMA helps improve PTSD symptoms better than just therapy alone. MDMA is a psychoactive drug, which means it affects the brain and can change mood or feelings.

Participants will have 10 therapy sessions over two weeks. They will take either 100 mg of MDMA or a placebo during the second session. After treatment, their PTSD symptoms will be checked with an interview one month later.

  • Study lasts a few weeks, including 10 therapy sessions.
  • Participants will take either MDMA or a placebo during the second session.
  • Safety and health are important, and participants must meet certain health criteria.
Print
Study details
    Post Traumatic Stress Disorder

NCT07288151

Emory University

17 October 2026

Contact a study center
Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race*
Are you a healthy volunteer
Ethnicity*
Are you a healthy volunteer
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.