This study looks at how Parkinson's Disease (PD) changes over time in patients who still have movement problems despite taking their usual PD medications. Parkinson's Disease affects the brain, causing issues like shaking, slow movement, and trouble with balance or walking. The study will observe patients without changing their current treatments. Participants will continue their normal care as doctors see fit.

Researchers will gather information from December 2025 to December 2032, and each participant may stay in the study for up to 5 years. They'll collect various data such as age, gender, medical history, and medication use. They'll also look at symptoms like shaking, mood changes, and sleep problems, and gather genetic information.

• The study is observational, meaning no new treatments will be given.
• Participants will need to provide information through medical records, diaries, and possibly blood samples.
• The study lasts up to 5 years, with data collection through visits and questionnaires.