Image

A Study to Evaluate TNX-102 SL Monotherapy Versus Placebo in Participants With Major Depressive Disorder (MDD)

Comparing TNX-102 SL to placebo in major depression treatment study.

Recruiting
18 years and older
All
Phase 2
  • Simplified description (AI rewritten)
  • Technical description (Original)

This study is checking if a medicine called TNX-102 SL helps adults with Major Depressive Disorder (MDD). MDD is a condition where people feel extremely sad for a long time. TNX-102 SL will be compared to a placebo, which is a pill that looks the same but has no medicine. This helps scientists see if TNX-102 SL really works.

To join this study, you need to have MDD for 6 weeks to 18 months and understand English. People with certain other mental health problems or those who haven't been helped by at least two different antidepressants before are not eligible.

  • Duration: The study lasts for 6 weeks with medicine taken at bedtime.
  • Visits: Participants need to visit the clinic every 2 weeks for checkups and tests.
  • Risks: Possible side effects are being monitored to ensure safety.

This study helps researchers learn about TNX-102 SL's effects and any medical issues it might cause.

Print
Study details
    Major Depressive Episode (MDE)
    Major Depressive Disorder (MDD)
    Depression

NCT07621237

Tonix Pharmaceuticals, Inc.

17 October 2026

Contact a study center
Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team

Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Race*
Are you a healthy volunteer
Ethnicity*
Are you a healthy volunteer
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.