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An Open-Label Study to Evaluate PF-07994525 in Participants With Advanced Cancers

Study testing PF-07994525 for advanced cancer patients.

Recruiting
18 years and older
All
Phase 1

This study tests a new medicine, **PF-07994525**, to see if it's safe and helps people with advanced cancers, like Multiple Myeloma (MM). **Multiple Myeloma** is a cancer of plasma cells, which are a type of white blood cell that helps fight infections. The study has two parts: Part 1 finds the right dose, and Part 2 checks how well it works and its effects on the body.

**Eligibility:** You can join if you're 18 or older and have tried at least three other MM treatments without success. You need to be healthy enough to participate (determined by your doctor) and must not have certain other medical conditions like active infections or other types of blood cancers.

**Key Points to Consider:**

  • **Study Length:** The study has two parts but doesn't specify the total duration.
  • **Visits Needed:** Regular visits for monitoring, but details are not specified.
  • **Risks:** Possible side effects from treatment, participation requires being in good health.
Study details
    Advanced Malignancies
    Advanced Cancer

NCT07426757

Pfizer

17 October 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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