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A Study of Lurbinectedin in Combination With Durvalumab for the Treatment of Participants With ES-SCLC

Testing Lurbinectedin and Durvalumab for ES-SCLC treatment.

Recruiting
18 years and older
All
Phase 2

This study tests two drugs, **lurbinectedin** and **durvalumab**, for a type of lung cancer called **extensive stage small cell lung cancer (ES-SCLC)**. This cancer has spread a lot and is usually treated first with a mix of medicines, including **platinum-based chemotherapy**. If the cancer doesn't get worse after the first treatment, the study checks how safe and effective the combination of lurbinectedin and durvalumab is as a continued treatment.

To join, you must have ES-SCLC confirmed by tests, completed 4 cycles of the first treatment, and have a life expectancy of at least 12 weeks. You should not have other serious health conditions like certain lung diseases, other cancers, or be pregnant.

  • The study involves using two specific drugs after initial treatment if the cancer hasn’t progressed.
  • You need to complete 4 cycles of initial treatment to qualify for this study.
  • It's important to discuss potential risks and benefits with your doctor before participating.
Study details
    Extensive-stage Small-cell Lung Cancer

NCT07459634

Jazz Pharmaceuticals

17 October 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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