This study is about how often to change the bandage on a special tube called a Peripherally Inserted Central Catheter (PICC). This tube is important for people with cancer like colon or pancreas cancer, as it helps deliver chemotherapy, which is cancer medicine, safely into their bodies. The study is trying to see if changing the bandage every 7 days (weekly) or every 14 days (biweekly) is safer and better for the skin.

Sometimes, changing bandages too often can hurt the skin, especially in people with sensitive skin due to cancer treatments. This is called Medical Adhesive-Related Skin Injury (MARSI). The study will include 150 adults who need these tubes for their cancer treatment. They will be observed over at least 6 cycles of chemotherapy, which may last up to 168 days.

• Participants are split into two groups: weekly and biweekly dressing changes.
• The study lasts up to 168 days (12 chemotherapy sessions).
• Participants will be checked for skin safety and how well the tube works.

Those interested should be adults with colon or pancreas cancer needing a PICC and be able to follow study instructions. Participants will be monitored for any complications and their satisfaction with the care they receive.