Pancreatic ductal adenocarcinoma is a severe type of cancer. About 40% of patients have a form called locally advanced pancreatic cancer (LAPC) that can't be removed with surgery. This study is testing a special treatment called radionuclide therapy (RNT). Instead of using beams from outside the body, RNT uses tiny particles called ³²P microparticles that are placed right into the tumor. These particles release strong radiation that can destroy cancer cells more effectively and safely. The treatment is given using a CT scan to guide the placement, ensuring it's done precisely.

This study will check if this method is safe and works well. The main concern is to see how many serious side effects happen within 90 days of treatment. People in the study will also continue their usual cancer treatment and will have regular check-ups.

• This study includes 20 adult patients who must not have disease progression.
• The procedure is done under anesthesia and might have side effects.
• The study spans 90 days, focusing on safety and effectiveness.