Image

Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.

We're studying RYZ401 for solid tumors with SSTRs.

Recruiting
18 years and older
All
Phase 1

This study is exploring a new drug, RYZ401, for people with certain types of solid tumors. These tumors have something called SSTRs, which are special protein markers found in some cancers. The main goal is to find the best dose and see how safe it is, as well as how well it works.

Eligibility: To join, you must be at least 18 years old and have certain advanced cancers. These include neuroendocrine tumors (NETs) from places like the stomach, pancreas, lungs, and more. There are two groups in this study: Dose Escalation and Dose Expansion. To qualify, your tumor must be SSTR-positive, which means it shows up on a special scan.

Exclusion: You cannot participate if you've had certain treatments before, like some radiation therapies, organ transplants, or have serious health issues like severe heart disease or uncontrolled diabetes.

  • The study involves finding the best dose and checking safety.
  • Participants must be over 18 and have specific advanced tumors.
  • Can't join if you've had certain past treatments or have major health concerns.
Study details
    GEP-NET
    Gastroenteropancreatic Neuroendocrine Tumor
    Gastroenteropancreatic Neuroendocrine Tumor Disease
    Neuroendocrine Tumors
    Carcinoid
    Carcinoid Tumor
    Pancreatic NET
    Solid Tumor
    Somatostatin Receptor

NCT07165132

RayzeBio, Inc.

31 July 2026

Step 1 Get in touch with the nearest study center
We have submitted the contact information you provided to the research team at {{SITE_NAME}}. A copy of the message has been sent to your email for your records.
Would you like to be notified about other trials? Sign up for Patient Notification Services.
Sign up

Send a message

Enter your contact details to connect with study team


Email

View email

Phone

Phone country flag

View phone
Investigator Avatar

Primary Contact

  Other languages supported:

First name*
Last name*
Email*
Phone number*
Other language

FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
Add a private note
  • abc Select a piece of text.
  • Add notes visible only to you.
  • Send it to people through a passcode protected link.