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SBRT Followed by Ipilimumab N01, Sintilimab, Nab-Paclitaxel and Gemcitabine for Locally Advanced Pancreatic Cancer

Exploring new treatments for advanced pancreatic cancer.

Recruiting
18-75 years
All
Phase 2

Study Overview: This study looks at a treatment plan for people with advanced pancreatic cancer. It combines a special type of radiation called stereotactic body radiotherapy (SBRT) with a mix of drugs: ipilimumab N01, sintilimab, nab-paclitaxel, and gemcitabine. The goal is to see if this treatment helps stop the cancer from growing and if it’s safe.

Key Points:

  • Participants will get SBRT followed by drug treatments over several weeks, with regular check-ups.
  • Eligible people must be 18-75 years old, have advanced pancreatic cancer without spread to other organs, and meet other health criteria.
  • Regular monitoring will check if the cancer stops growing and assess any side effects.

Participants must be willing to follow all study guidelines and not be involved in other cancer trials. The main focus is on how long people live without their cancer getting worse (progression-free survival), alongside other health measures. Safety will be closely watched throughout.

Study details
    Pancreatic Cancer

NCT07683221

Shandong Cancer Hospital and Institute

17 October 2026

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Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

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Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

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Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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