**Association Between Chronic Psychological Stress and Disease Course Outcomes in Pancreatic Cancer** This study looks at how stress affects people with pancreatic cancer. *Pancreatic cancer* is a serious disease in the pancreas, a gland that helps with digestion. *Psychological stress* includes feelings like anxiety (being very worried), depression (feeling very sad), and sleep problems. The researchers believe that people with more stress might have worse outcomes, like cancer coming back or not responding well to treatment. **Key Points:** - **Participation Requirements:** Participants need to be 18 or older, have pancreatic cancer, and be able to fill out questionnaires. - **Study Procedures:** You'll answer questions about your mood and sleep regularly, and a small blood sample will be taken to check stress levels. - **Duration and Follow-Up:** The study involves regular check-ins at different treatment stages and throughout a year to see how you’re doing. This study won't change your treatment, but it helps doctors understand more about stress and cancer. Participants will not receive specific treatments or medication changes as a result of the study, and it requires time for filling out questionnaires and follow-ups.