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A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors

Testing AGX101's safety and effects in advanced cancer patients.

Recruiting
18 years and older
All
Phase 1

AGX101 is a special kind of cancer medicine called an antibody-drug conjugate (ADC) given through a vein to help treat advanced solid tumors, which are hard lumps caused by cancer. This study is checking if AGX101 is safe and how well it works. People in the study will get the medicine every 3, 6, or 9 weeks and can continue until their disease worsens, they have bad side effects, or they choose to stop. After treatment, there will be a final visit and two follow-up calls within 90 days.

  • Study Visits: Participants will have regular visits for treatment and follow-ups.
  • Eligibility: Patients must have advanced cancer and be unable to have surgery, among other criteria.
  • Risks: Possible side effects and need to meet certain health conditions to join.

To join, participants need to have certain types of cancer, must have tried other treatments, and be in good overall health. Some people, like those with certain infections or recent surgeries, can't participate. It's important to discuss with a doctor to see if this study is the right choice.

Study details
    Cancer
    Advanced Cancer
    Locally Advanced Carcinoma
    Metastatic Solid Tumor
    Breast Cancer
    Prostate Cancer
    Colorectal Cancer
    Pancreatic Cancer
    Liver Cancer
    Angiosarcoma
    Solid Tumor

NCT06440005

Angiex, Inc.

12 September 2026

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FAQs

Learn more about clinical trials

What is a clinical trial?

A clinical trial is a study designed to test specific interventions or treatments' effectiveness and safety, paving the way for new, innovative healthcare solutions.

Why should I take part in a clinical trial?

Participating in a clinical trial provides early access to potentially effective treatments and directly contributes to the healthcare advancements that benefit us all.

How long does a clinical trial take place?

The duration of clinical trials varies. Some trials last weeks, some years, depending on the phase and intention of the trial.

Do I get compensated for taking part in clinical trials?

Compensation varies per trial. Some offer payment or reimbursement for time and travel, while others may not.

How safe are clinical trials?

Clinical trials follow strict ethical guidelines and protocols to safeguard participants' health. They are closely monitored and safety reviewed regularly.
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