Pancreatoduodenectomy (PD), also called the Whipple procedure, is a complex surgery done for pancreatic and other related cancers. This study compares two ways to perform this surgery: robotic-assisted (using machines) and open surgery (traditional method). The study is happening in Spain and involves several hospitals. Patients will be chosen randomly for either robotic or open surgery.

The study will last two years, with follow-up for three years after surgery. The main goal is to check complications within 90 days post-surgery using a tool called the Comprehensive Complication Index (CCI). Other things like hospital stay, costs, and quality of life will be measured too.

Key Points:

• Participation requires being 18 or older and needing planned PD surgery.
• The study compares robotic and open surgery methods.
• Participants are followed for three years after surgery.

This study could help determine the safest and most effective surgery method, leading to better recovery and health outcomes for patients.