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Auricular Point Stimulation Plus Dexamethasone for Nausea and Vomiting Caused by Gemcitabine Plus Paclitaxel

Testing ear point therapy and medication for chemo-related nausea and vomiting.

Recruiting
18-85 years
All
Phase 2

This study looks at whether auricular point stimulation (a treatment involving pressing seeds on the ear) plus dexamethasone (a medication that reduces inflammation) can help stop or lessen nausea and vomiting caused by chemotherapy drugs gemcitabine and paclitaxel in pancreatic cancer treatment. The study also checks if this method helps with symptoms like loss of appetite and stomach problems caused by using too many anti-nausea drugs. Participants will receive ear seed therapy and an injection of dexamethasone before chemotherapy and will stimulate their ear points daily for five days. They will track their nausea, vomiting, and stomach function during this time. Oral anti-nausea medicine will be ready if needed.

  • Study lasts for 5 days with daily self-administered treatments.
  • Participants must be 18-85 years old and undergoing specific chemotherapy for pancreatic cancer.
  • Participants will monitor and report their symptoms daily.
Study details
    Nausea and Vomiting Caused by Chemotherapy

NCT07537660

Second Affiliated Hospital, School of Medicine, Zhejiang University

31 July 2026

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